"What happens when Marvel's favorite heroes hit the centennial mark? It's 2061, and the world of the Fantastic Four has turned upside-down, complete with the granddaughter of Doom and the Richards-Banner twins! It's 100 years after Spider-Man's creation, and the Kingpin has stolen Spidey's ultra-powerful techno-symbiote suit! Have the X-Men of 2061 achieved Xavier's dream of mutants and humans living in harmony? How will the Avengers of 2061 cope following the failed Badoon invasion of Earth and America's disappearance into the Negative Zone? And just in time for the release of their seventh epic motion picture, the Guardians of the Galaxy take on the Silver Galactus!"--Unedited summary from the book.

Contains material originally published in individual magazine form as 100th anniversary specials.

100th anniversary special: Fantastic Four /writer: Jen Van Meter, artist: Joanna Estep, letterer: VC's Joe Sabino -- 100th anniversary special: Spider-man / writer: Sean Ryan, artist: In-Hyuk Lee, letterer: VC's Clayton Cowles -- 100th anniversary special: X-Men / writer: Robin Furth, artist: Jason Masters, colorists: James Campbell & Veronica Gandini, letterer: VC's Cory Petit -- 100th anniversary special: Avengers / writer, artist, letterer & cover art: James Stokoe -- 100th anniversary special: Guardians of the Galaxy / writers: Andy Lanning & Ron Marz, artist: Gustavo Duarte, colorist: Edgar Delgado, letterer: VC's Joe Sabino.