House is serving a prison sentence for driving his car into Cuddy's living room, and when his sentence ends early, he finds the Diagnostic Medicine Department has gone through a transition in his absence and he must deal with a new chain of command and personnel changes to his staff. Together, House and his new team take on the most baffling medical cases yet, and face challenges of both the mind and heart as this television phenomenon comes to a close.

Contains all 22 episodes from the eighth and final season. Originally broadcast as 22 episodes of the 2011-2012 television program. Special features: House, M.D. swan song; The doctor directs: behind the scenes with Hugh Laurie; Everybody dies: a postmortem.

Disc 1.Twenty vicodin -- Transplant -- Charity case -- Risky business -- The confession -- Disc 2. Parents -- Dead and buried -- Perils of paranoia -- Better half -- Runaways -- Disc 3. Nobody's fault -- Chase -- Man of the house -- Love is blind -- Blowing the whistle -- Disc 4. Gut check -- We need the eggs -- Body and soul -- The C-word -- Post mortem -- Disc 5. Holding on -- Everybody dies.