Genome organization, replication, and transcription of filoviruses / Elke Mühlberger -- Structure of viral proteins / Winfried Weissenhorn -- Structural and functional polymorphism of the glycoproteins of filoviruses / Viktor E. Volchkov, Valentina A. Volchkova, Olga Dolnik, Heinz Feldmann, and Hans-Dieter Klenk -- Molecular mechanisms of filovirus entry / Stephen Y. Chan and Mark A. Goldsmith -- Roles of filoviral matrix- and glycoproteins in the viral life cycle / Gabriele Neumann, Takeshi Noda, Ayato Takada, Luke D. Jasenosky, and Yoshihiro Kawaoka -- Virus maturation / Larissa Kolesnikova and Stephan Becker -- Flilovirus pathogenesis in nonhuman primates / Thomas Larsen, Kelly J. Davis, and Lisa E. Hensley -- Ebola virus infection in the guinea pig / Elena Ryabchikova, Margarita Smolina, Antonina Grajdanteva, and Jurii Rassadkin -- Pathogenesis of filovirus infection in mice / Mike Bray -- The role of endothelial cells in filovirus hemorrhagic fever -- Hans-Joachim Schnittler, Ute Ströher, Tatiana Afanasieva, and Heinz Feldmann -- Modulation of innate immunity by filoviruses / Christopher F. Basler and Peter Palese -- Cellular and molecular mechanismsof ebola pathogenicity and approaches to vaccine development / Gary J. Nabel, Nancy J. Sullivan, and Zhi-Yong Yang.