Prologue: Different Strokes --3 -- Part 1 Benefits -- 1 Pregnant Mare's Lesson -- 23 -- 2 Leaving the Dark Ages Behind, Mostly -- 39 -- Part 2 Risks -- 3 Fat is in the Fire -- 71 -- 4 Too Sweet to Be True -- 85 -- 5 Cold Comfort -- 96 -- 6 Getting Risks Right -- 102 -- 7 Most Vulnerable Patients -- 126 -- 8 Enter Doctor Faustus -- 139 -- 9 Imperfect Measures -- 149 -- 10 Whose Risk Is It, Anyway? -- 160 -- 11 A Balancing Act -- 172 -- Part 3 Costs -- 12 Live Cheap or Die -- 189 -- 13 Filling the Pipeline -- 198 -- 14 What the Traffic Will Bear -- 217 -- 15 Navigating the Third Dimension -- 235 -- Part 4 Information -- 16 Signals, Noise, and the Big Void -- 269 -- 17 Informational Kudzu -- 292 -- 18 Devising an Antidote -- 313 -- 19 Emperor's Fashion Critics -- 339 -- 20 Same Language, Different Accents -- 348 -- Part 5 Policy -- 21 Pulling the Facts Together -- 359 -- 22 Turning Knowledge into Action -- 388 -- 23 Markets and Medicines -- 401 -- Epilogue: The Triple-Edged Sword -- 417.