Introduction: The Beginning of Regulation --ix -- Prologue: The Challenge -- 3 -- Chapter 1. Dr. Wiley's Time -- 11 -- Chapter 2. Commerce, Commerce, Commerce -- 19 -- Chapter 3. Progressive Era -- 35 -- Chapter 4. Law Succeeds, and Fails -- 56 -- Chapter 5. Capitalism in Crisis -- 72 -- Chapter 6. Birth of the Modern Pharmaceutical Trade -- 95 -- Chapter 7. New Drugs, New Problems -- 108 -- Chapter 8. Industry Ascendant -- 117 -- Chapter 9. Grand Bargain -- 129 -- Chapter 10. Thalidomide -- 144 -- Chapter 11. Science Meets Policy -- 166 -- Chapter 12. Partisan Politics -- 178 -- Chapter 13. Limits of Policy -- 202 -- Chapter 14. Deregulation -- 210 -- Chapter 15. Medical Officer -- 224 -- Chapter 16. Modern Plague -- 236 -- Chapter 17. A Progressive -- 255 -- Chapter 18. Drug Lag Revisited -- 276 -- Chapter 19. An Anti-regulatory Campaign -- 291 -- Chapter 20. Argument Is Joined -- 309 -- Chapter 21. Old-fashioned Politics -- 325 -- Epilogue: Greed and Goodness -- 338.