Calloway reminds us that neither Indians nor Colonists were a monolithic group resulting in a more nuanced appreciation for the complexity of cultural relationships in Colonial America. He provides an essential starting point for studying the interaction of Europeans and Indians in early American life.

Introduction : the kaleidoscope of early America --1. Imaging and creating a new world -- 2. Healing and disease -- 3. The stuff of life -- 4. A world of dreams and bibles -- 5. New world warfare and a new world of war -- 6. New world diplomacy and new world foreign policies -- 7. New nomads and true nomads -- 8. Crossing and merging frontiers -- 9. New peoples and new societies -- Conclusion : new Americans and first Americans.