"Textbook in pediatric pharmacology and provides evidence-based guidelines for safe, effective, and rational drug therapy in newborns, children, and adolescents"-- Provided by publisher.

Revision of: Neonatal and pediatric pharmacology / [edited by] Sumner J. Yaffe, Jacob V. Aranda. c2010. 4th ed.

Section I:General principles. Clinical trials involving children: history, rationale, regulatory framework, and technical considerations ; Clinical pharmacokinetics in infants and children ; Developmental pharmacodynamics, receptor function, and drug actions in newborns and children ; Drug absorption, distribution, metabolsim, excretion, and transporters in newborns and children ; Pharmacogenetics, pharmacogenomics, and pharmacoproteomics in newborns and children ; Ethics of drug research in newborns and children ; Precision medicie and therapeutic drug monitoring ; Drug formulations for children -- Section II: Pharmacology in special settings and population: the newborn. Role of placenta in drug metabolism and drug transfer ; Maternal medications during pregnancy and lactation ; Principles of neonatal pharmacology ; Renal function and excretion of drugs in the newborn ; Neuroprotective drugs and perinatal brain injury ; Pharmacologic agents for neonatal hyperbilirubinemia ; Pharmacologic treatment of neonatal apnea -- Section III: Pharmacology in special settings and population. Therapeutic applications in pediatric intensive care ; Drug therapy in the pediatric emergency department ; Topical medications ; Ophthalmologic drugs in infants and children -- Section IV: Antimicrobial pharmacology. Penicillins, cephalosporins, and other [beta]-lactams ; Glycopeptides, lipoglycopeptides, and lipopeptides ; Aminoglycosides ; Macrolides, clindamycin, and oxazolidinones ; Fluoroquinolones ; Sulfonamides, dihydrofolate reductase inhibitors, and dapsone ; Tetracyclines, chloramphenicol, and metronidazole ; Antimalarials ; Anthelminthics drugs in children ; Antimycobacterial drugs (mycobacterium tuberculosis and atypical mycobacteria) ; Antifungal agents ; Antivirals in newborns and children ; Pharmacology of antiretroviral drugs in pregnant and breastfeeding women and their newborns -- Section V: Neuropharmacology. Anticonvulsants ; Antidepressants and mood stabilizers ; Stimulants, ADHD treatments, and antipsychotics ; Analgesics and sedatives ; Pharmacologic management of neonatal abstinence syndrome ; Local anesthetic agents for regional and superficial anesthesia in infants, children and adolescents -- Section VI: Immunopharmacology, allergy, and inflammation. Nonsteroida anti-inflammatory drugs ; Antihistamine drugs ; Antiasthmatics ; Immunosuppressive and immunomodulatory drugs -- Section VII: Pharmacology of biologic drugs. Microbial therapeutics: beyond probiotics ; Monoclonal antibiotics ; Stem cells ; Drugs, lung development, and pulmonary surfactant ; Childhood vaccines -- Section VIII: Cardiorenal drugs. Neonatal cardiovascular pharmacology ; Antiarrhythmic drugs: disorders of cardiac rhythm and pharmacologic management ; Antihypertensive drugs ; Diuretics -- Section IX: Gastrointestinal pharmacology. Gastrointestinal drugs ; Drugs in inflammatory bowel disease -- Section X: Endocrine and hematologic pharmacology. Glucocorticoids ; Insulin and diabetes ; Growth hormone ; Thyroid hormones ; Hematologic agents ; Clinical pharmacology of antineoplastic drugs -- Section XI: Nutritional pharmacology, pharmacotoxidromes, adverse drug reactions, and interactions. Nutrient supplements ; Herbal drugs in children ; Pediatric poisonings and antidotes ; Adverse drug reactions in newborns and children ; Medication errors in children ; Drug interactions in newborns and children -- Appendix A1: Neonatal drug formulary -- Appendix A2: Pediatric drug formulary.