Epidemiologic aspects of epilepsy /Christine Lineham and Anne T. Berg -- The Natural history of seizures / Ding Ding and W. Allen Hauser -- Experimental models of seizures and mechanisms of status epilepticus and epileptogenesis / Timothy A. Benke and Molly M. Huntsman, and Amy Brooks-Kayal -- Genetics of the epilepsies / Jocelyn F. Bautista and Anne Anderson -- Pictorial atlas of epilepsy substrates / Ajay Gupta and Richard A. Prayson -- Neurophysiologic basis of the electroencephalogram / Erwin-Josef Speckmann, Christian E. Elger, and Ulrich Altrup -- Localization and field determination in electroencephalography / Richard C. Burgess -- Electroencephalographic atlas of epileptiform abnormalities / Soheyl Noachtar and Elaine Wyllie -- Terminology for seizures and epilepsies / Tobias Loddenkemper and Anne T. Berg -- Epileptic auras / Norman K. So -- Focal motor seizures / Andreas V. Alexopoulos and Stephen E. Jones -- Focal seizures with impaired consciousness / Lara Jehi and Prakash Kotagal -- Autonomic seizures, autonomic effects of seizures, and SUDEP / Brian D. Moseley and Elaine C. Wirrell -- Generalized motor seizures / William O. Tatum IV -- Absence seizures / Emily Robbins and Dennis J. Dlugos -- Epileptic spasms / Kelly G. Knupp and Ingrid Tuxhorn -- Presumed genetic and benign focal epilepsies of childhood / Elaine C. Wirrell, Carol S. Camfield, and Peter R. Camfield -- Idiopathic generalized epilepsy syndromes of childhood and adolescence / Stephen Hantus -- Progressive and infantile myoclonic epilepsies / Bernd Axel Neubauer, Andreas Hahn, and Ingrid Tuxhorn -- Encephalopathic generalized epilepsy and Lennox-gastaut syndrome / S. Parrish Winesett and William O. Tatum IV -- Continuous spike-and-wave during sleep including Landau-Kleffner syndrome / Iván Sánchez Fernández and Tobias Loddenkemper -- Epilepsy with reflex seizures / Dorothee Kasteleijn-Nolst Trenite and Frederick Andermann -- Rasmussen syndrome / François Dubeau -- Temporal lobe epilepsies / Norman K. So -- The Extratemporal epilepsies / Carla LoPinto-Khoury and Michael R. Sperling -- Malformations of cortical development and epilepsy / Ghayda M. Mirzaa, Ruben Kuzniecky, and Renzo Guerrini -- Brain tumors and epilepsy / Lara Jehi and Ingmar Blumcke -- Post traumatic epilepsy / Jay R. Gavvala and Stephen U. Schuele -- Epilepsy in the setting of cerebrovascular disease / Stephen Hantus, Neil Friedman, and Bernd Pohlmann-Eden -- Epilepsy in the setting of neurocutaneous syndromes / Ajay Gupta -- Epilepsy in the setting of inherited metabolic and mitochondrial disorders / Sumit Parikh, Douglas R. Nordli, Jr., and Darryl C. De Vivo -- Central nervous system infections and epilepsy / Gagandeep Singh and J.M.K. Murthy -- Autoimmune issues in epilepsy / Ahsan N.V. Moosa -- Febrile seizures / Syndi A. Seinfeld and Michael Duchowny -- Neonatal seizures / Kevin Chapman, Eli M. Mizrahi, and Robert Ryan Clancy -- Seizures associated with nonneurologic medical conditions / Stephen Eisenschenk, Jean E. Cibula, and Maria I. Hella -- Sleep and epilepsy / Nancy Foldvary-Schaefer and Silvia Neme-Mercante -- Status epilepticus / Howard P. Goodkin and James J. Riviello, Jr. -- Application of electroencephalography in the intensive care setting / Stephen Hantus, Nicholas S. Abend, and Deepak Lachwani -- Psychogenic nonepileptic seizures / W. Curt LaFrance, Jr. and Hamada I. Hamid -- Other nonepileptic paroxysmal disorders / Elia M. Pestana Knight and John M. Pellock -- Antiepileptic drug development and experimental models / Melissa L. Barker-Haliski and H. Steve White -- Mechanisms of action of antiepileptic drugs / Michael A. Rogawski and José Enrique Cavazos -- Pharmacokinetics and drug interactions / Gail D. Anderson -- Initiation and discontinuation of antiepileptic drugs / Varda Gross-Tsur, Ruth C. Shinnar, and Shlomo Shinnar -- Hormones, catamenial epilepsy, sexual function, and reproductive and bone health in epilepsy / Scott J. Stevens and Cynthia L. Harden -- Treatment of epilepsy during pregnancy / Page B. Pennell -- Individual approach to laboratory monitoring of antiepileptic drugs / Svein I. Johannessen and Philip N. Patsalos -- Genetic influences on responses to drugs used to treat epilepsy / Thomas N. Ferraro -- Benzodiazepines / L. John Greenfield, Jr., Kinshuk Sahaya, Bashir Shihabuddin, Elizabeth I. Tietz, and Howard C. Rosenberg -- Carbamazepine, oxcarbazepine, and eslicarbazepine / Carlos A.M. Guerreiro, Marilisa M. Guerreiro, and Scott Mintzer -- Ethosuximide / Andres M. Kanner and Ramses Ribot -- Ezogabine (Retigabine) / Scott Mintzer -- Felbamate / Edward Faught -- Gabapentin and pregabalin / Piero Perucca and John M. Dopp -- Lacosamide / Raj D. Sheth -- Lamotrigine / Barry E. Gidal and John M. Stern -- Levetiracetam / Joseph I. Sirven, Katherine H. Noe, and Matthew T. Hoerth -- Perampanel / Gregory L. Krauss and Barry E. Gidal -- Phenobarbital and primodone / Mark C. Spitz, Jacquelyn L. Bainbridge, and Pei Shieen Wong -- Phenytoin and fosphenytoin / Jeannine M. Conway, Diego A. Morita, and Tracy A. Glauser -- Rufinamide / Gregory L. Krauss and Rama K. Maganti -- Topiramate / William E. Rosenfeld -- Valproate / Angela K. Birnbaum and Susan E. Marino -- Vigabatrin / Kelly G. Knupp and Elizabeth A. Thiele -- Zonisamide / Timothy E. Weltry -- Adrenocorticotropin and steroids / Cristina Go and O. Carter Snead III -- Antiepileptic drugs in clinical development / Deana M. Gazzola, Norman Delanty, and Jacqueline A. French -- Less commonly used antiepileptic drugs / Robert T. Wechsler and Basim M. Uthman -- Dietary therapies for epilepsy / Eric H.W. Kossoff -- Vagus nerve stimulation therapy / James W. Wheless -- Issues of medical intractability for surgical candidacy / Samuel Wiebe and Nathalie Jetté -- Magnetic resonance imaging in evaluation for epilepsy surgery / Ahsan N.V. Moosa and Paul M. Ruggieri -- Video-EEG monitoring in the presurgical evaluation / Jeffrey William Britton -- Nuclear imaging (PET, SPECT) / William Davis Gaillard -- Magnetoencephalography / Richard C. Burgess and John C. Mosher -- MRI postprocessing techniques and clinical applications / Z. Irene Wang, Stephen E. Jones, and Andrea Bernasconi -- Diffusion tensor imaging (DTI) and EEG-Correlated FMRI / Beate Diehl and Louis Lemieux -- Language and memory mapping / Jeffrey R. Binder and Chad Carlson -- Mapping motor function / Martin Staudt, Juan Carlos Bulacio, and Dileep R. Nair -- Strategies and indications for evaluation with invasive electrodes / Jorge Alvaro González-Martinez, William E. Bingaman, Patrick Chauvel, and Imad M. Najm -- Surgery for medically refractory temporal lobe epilepsy / Sumeet Vadera, William E. Bingaman, and Imad M. Najm -- Surgery for focal cortical dysplasias / Imad M. Najm, Andre Palmini, and William E. Bingaman -- Hemispherectomy: indications, procedures, and outcome / Ahsan N.V. Moosa, Jorge Alvaro González-Martinez, Ajay Gupta, and William E. Bingaman -- Surgical approach in multilesional or multilobar epilepsies / Elia M. Pestana Knight, Ajay Gupta, and Elaine Wyllie -- Surgical approach in nonlesional cases / Deepak Lachhwani and Jorge Alvaro González-Martinez -- Hypothalamic hamartoma / John F. Kerrigan -- Corpus callosotomy and multiple subpial transection / Michael C. Smith, Richard W. Byrne, and Andres M. Kanner -- Special considerations in children / Ajay Gupta and Elaine Wyllie -- Outcome and complications of epilepsy surgery / Lara Jehi, Jorge Alvaro González-Martinez, and William E. Bingaman -- Electrical stimulation for the treatment of epilepsy / Wei Hu, S. Matthew Stead, and Gregory A. Worrell -- Cognitive effects of epilepsy and its treatments / Kimford J. Meador -- Psychiatric comorbidity of epilepsy / Beth A. Leeman-Markowski and Steven C. Schachter -- Driving and social issues in epilepsy / Amy Z. Crepeau and joseph F. Drazkowski -- Quality of life with epilepsy / Tatiana Falcone and Allyson M. Palombaro -- A Mother's perspective / Susan Axelrod -- Indications for antiepileptic drugs sanctioned by the United States food and drug administration / Kay C. Kyllonen.