Product Description: A new and revised version of this best-selling reference! For over eighteen years, best-selling Cancer Nursing: Principles and Practice has provided oncology nurses with the latest information on new trends in the rapidly changing science of oncology. Now, in its Seventh Edition, Cancer Nursing has been completely revised and updated to reflect key new developments. New topics covered include targeted therapy, hypersensitivity reactions, mucositis, and family and caregiver issues. With 27 new chapters featuring insights from key authors, the Seventh Edition is a must-have resource for every oncology nurse.

Preface -- Editors -- Contributors -- Part 1: Cancer Problem -- 1: Biology of cancer / Carrie J Merkle -- Introduction -- Theories and research models of tumor development -- Properties of cancer and transformed cells, genetic influences associated with cancer -- Cell cycle -- Apoptosis -- Metastasis -- Conclusion -- References -- 2: Immunology / Janice Post-White; Susan M Bauer-Wu -- Introduction -- Overview -- Components of the immune system -- Mechanisms of adaptive immunity -- Tissue destruction from immune responses -- Factors affecting immune responses -- Implication for nursing practice -- References -- 3: Epidemiology / Alecia Malin Fair -- Introduction -- Basic considerations in epidemiological research -- Causes of cancer -- Biomakers -- Host characteristics influencing cancer susceptibility -- Psychoneuroimmunology and cancer risk -- Application of epidemiology to nursing practice -- References -- Part 2: Prevention, Detection, and Diagnosis -- 4: Cultural diversity among individuals with cancer / Joanne K Itano -- Introduction -- Ethnicity and cancer -- Nursing issues -- Resources -- Conclusion -- References -- 5: Dynamics of cancer prevention / Judith J Smith; Barbara K Dunn -- Introduction -- Cancer prevention principles -- Cancer prevention strategies -- Cancer prevention and public policy -- Cancer prevention challenges -- Nursing implications -- References -- 6: Screening and detection for asymptomatic individuals / Suzanne M Mahon -- Introduction -- Conceptual considerations in cancer screening -- Cancer risk assessment: the first step in the cancer screening process -- Oral communication of risk -- -- Measures of the accuracy of screening tests -- Implementing cancer screening -- Nursing implications -- Conclusion -- References -- 7: Genetic risk and hereditary cancer syndromes / Jennifer T Loud; Sadie P Hutson -- Introduction -- Cancer nursing practice and hereditary cancer syndromes -- Vocabulary of hereditary cancer syndromes for oncology nurses -- Characteristics of hereditary cancer syndromes -- Ethical, legal and social implications of predisposition genetic testing for hereditary cancer syndromes -- Risk assessment of cancer susceptibility -- Cancer risk assessment models -- Genetic counseling -- Selected hereditary cancer syndromes -- Hereditary breast and ovarian cancer syndromes -- Hereditary colorectal cancer syndromes -- Multiple endocrine neoplasia -- Li-Fraumeni syndrome -- Future direction of nursing practice and research -- Conclusion -- References -- Appendix 7-1: Cancer genetics resources: an organizational guide -- 8: Diagnostic evaluation, classification, and staging / Wendy H Vogel -- Introduction -- Goals and factors affecting the diagnostic approach -- Diagnostic approach -- Classification and nomenclature -- Staging and grading classifications -- Nursing implications -- Future trends -- Conclusion -- References -- Part 3: Treatment -- 9: Quality of life as an outcome of cancer care / Carol Estwing Ferrans; Eileen Danaher Hacker -- Introduction -- Quality of life as a prognostic indicator -- Using quality of life information in cancer care -- Using quality of life questionnaires in clinical practice -- What is quality of life? -- Measuring quality of life -- Clinical significance -- Data collection in real time -- Populations presenting special challenges -- Conclusion -- References -- 10: Principles of cancer clinical trials / Anthony DeLaCruz; Mary S McCabe -- Overview -- Clinical trails process and implementation -- Nonclinical trial access to experimental agents: special access programs -- Protection of research participants -- Barriers to clinical trials participation -- Cancer clinical trials programs -- Current issues -- Current issues -- Future trends -- References -- 11: Surgical therapy / Theresa Wicklin Gillespie -- Introduction -- Roles of surgery in oncology care -- Clinical decision making in surgical therapy -- Impact of nursing care on surgical outcomes -- Trends in surgical oncology -- Special considerations for nursing care -- Conclusion -- References -- 12: Principles of radiation therapy / Tracey K Gosselin -- Introduction -- History of radiation therapy -- Goals of treatment approaches -- Applied radiation physics -- High-linear-energy-transfer and charged-particle radiation therapy -- Radiobiology -- Chemical and thermal modifiers of radiation -- Incidental and accidental radiation exposure -- Conclusion -- References -- 13: Radiation treatment planning / Susan Weiss Behrend -- Introduction -- Overview -- Simulation -- Planning/localization/imaging -- Principles of external beam radiation dosing/dosimetry -- Patient positioning and immobilization techniques -- Delivery of radiation therapy: machines and equipment -- Treatment delivery modalities -- Advanced topics: treatment delivery -- Conclusion -- References -- 14: Radiation therapy: toxicities and management / Marilyn L Haas -- Introduction -- Radiobiology -- Tissue and organ response to radiation -- Roles of nursing in radiation oncology -- General side effects of radiation -- Acute radiation toxicities and management: site specific -- Secondary malignancies -- Conclusion -- References -- 15: Cytotoxic chemotherapy: principles of therapy / Peter V Tortorice -- Historical perspective -- Cancer chemotherapy drug development -- Scientific basis of chemotherapy -- Cytotoxic drug-selection criteria -- Managing chemotherapy resistance -- Chemotherapy as a treatment for cancer -- Pharmacology of chemotherapeutic drugs -- Conclusion -- References -- 16: Chemotherapy: principles of administration / Gail M Wilkes -- Chemotherapy administration -- Drug administration -- Vascular access devices -- Conclusion -- References -- Appendix 16 A: Oral chemotherapy and hormonal agents -- 16 B: Intravenous chemotherapy agents -- 17: Chemotherapy toxicities and management /Dawn Camp-Sorrell -- Introduction -- Pretreatment evaluation: risk analysis -- Quality of life and chemotherapy toxicity -- Self-care -- Patient education and follow-up -- Chemotherapy toxicities -- Conclusion -- References -- 18: Principles and techniques of blood and marrow transplantation / Susan A. Ezzone -- Historical developments -- Hematopoiesis and transplant immunology -- Types of transplant -- Sources of stem cells -- Indications for transplant and survival outcomes(diseases treated) -- Patient evaluation -- Common preparative regimens -- Transplant course -- Site of care delivery -- Outpatient follow-up -- Future directions -- References. 19: Complications of hematopoietic cell transplantation / Lowell Anderson-Reitz -- Introduction -- Prophylactic support -- Peritransplant supportive care -- Evaluation and treatment of complications -- Acute complications -- Late complications -- Conclusion -- References -- 20: Biotheraphy / Paula M Muehlbauer -- Introduction -- Historical perspective -- Immunology overview -- Interleukin -- Interferons -- Bacillus calmette-guerin -- Imiquimod -- Cancer vaccines -- Adoptive cellular transfer therapy -- Conclusion -- References -- 21: Targeted therapy / Debra Wujcik -- Introduction -- Signal transduction -- Receptor kinase pathways -- Intracellular signaling kinase pathways -- Angiogenesis pathways -- Monoclonal antibodies -- Tyrosine kinase inhibitors -- Nursing management -- Future implications -- References -- 22: Gene therapy / Dale Halsey Lea -- Introduction -- Genetic disorders -- Principles and goals of gene therapy -- Vectors for gene transfer -- Future approaches to gene therapy -- Clinical protocols for gene therapy -- Ethical, social, and legal issues in gene therapy -- Practice implications for oncology nurses -- Conclusion -- References -- 23: Hematopoietic therapy / Colleen Lemoine; Barbara Holmes Gobel -- Introduction -- Hematopoietic growth factors -- Transfusion therapy -- Conclusion -- References -- 24: Complementary and alternative medicine (CAM) therapies in integrative oncology / Georgia Decker; Colleen O Lee -- Introduction -- CAM regulation -- Evidence-based practice -- Integrative oncology: efficacy and safety of commonly used modalities -- Symptom management -- Education -- Future trends -- References -- Part 4: Cancer Symptom Management -- 25: Evidence-based oncology nursing / Dana N Ruthledge -- Introduction -- Evidence-based nursing -- Framework: implementation of evidence-based practice -- Becoming a nurse who bases care upon evidence -- Conclusion -- References -- 26: Cancer-related distress / Marlene Zichi Cohen; Susan Bankston -- Introduction -- Historical perspective -- Language -- Incidence of distress associated with cancer -- Etiology of risk factors for distress -- Barriers to identification and treatment -- Special populations -- Clinical manifestations of distress -- Assessment of distress -- Therapeutic approaches and nursing care -- Conclusion -- References -- 27: Cancer pain management / Erin McMenamin -- Scope of the problem -- Epidemiology of cancer pain -- Etiology of cancer pain -- Physiological alterations -- Types of pain -- Clinical manifestations -- Assessment -- Pharmacological management of pain -- Interventional management of pain -- Nonpharmacological management of pain -- Conclusion -- References -- 28: Infection / Brenda K Shelton -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Assessment and grading -- Therapeutic approaches and nursing care -- Conclusion -- References -- 29: Bleeding / Anna Liza Rodriguez; Barbara Holmes Gobel -- Scope of the problem -- Physiology of bleeding -- Pathophysiology of bleeding -- Assessment for bleeding -- Therapeutic approaches and nursing care -- Conclusion -- References -- 30: Cancer-related fatigue / Sandra A Mitchell -- Scope of the problem -- Psychophysiological models of CRF -- Evaluation of the patient with cancer-related fatigue -- Interventions for fatigue -- Conclusion and future directions -- References -- 31: Hypersensitivity reactions to antineoplastic drugs / Barbara Holmes Gobel; Colleen O'Leary -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Therapeutic approaches and nursing care -- Conclusion -- References -- 32: Oral mucositis / Carlton G Brown -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Assessment and grading -- Therapeutic approaches and nursing care -- Conclusion -- References -- 33: Nutritional disturbances / Regina S Cunningham; Maureen B Huhmann -- Scope of the problem -- Normal nutritional physiology -- Pathophysiology -- Clinical manifestations -- Screening, assessment, and grading -- Therapeutic approaches and nursing care -- Conclusion -- References -- 34: Paraneoplastic syndromes / Kelly D Mayden -- Introduction -- Neurological paraneoplastic syndromes -- Endocrine paraneoplastic syndromes -- Hematologic paraneoplastic syndromes -- Renal paraneoplastic syndromes -- Miscellaneous paraneoplastic syndromes -- Conclusion -- References -- 35: Malignant effusions / Diane G Cope -- Introduction -- Pleural effusions -- Pericardial effusions -- Malignant peritoneal effusions -- Conclusion -- References -- 36: Sexual and reproductive dysfunction / Linda U Krebs -- Scope of the problem -- Physiological alterations -- Clinical manifestations: effect of cancer therapy on gonadal function -- Assessment -- Therapeutic approaches and nursing care -- Pregnancy and cancer -- Conclusion -- References. Part 5: Oncologic Emergencies -- 37: Cardiac tamponade / Roberta Kaplow -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Assessment -- Therapeutic approaches and nursing care -- Conclusion -- References -- 38: Disseminated intravascular coagulation / Barbara Holmes Gobel -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Assessment -- Therapeutic approaches and nursing care -- Conclusion -- References -- 39: Hypercalcemia of malignancy / Marcelle Kaplan -- Scope of the problem -- Physiological alterations -- Clinical manifestations of hypercalcemia -- Assessment -- Grading hypercalcemia in malignant disease -- Therapeutic approaches -- Nursing management -- Conclusion -- References -- 40: Septic shock / Colleen O'Leary -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Assessment and grading -- Therapeutic approaches and nursing care -- Conclusion -- References -- 41: Spinal cord compression / Anne Marie Flaherty -- Scope of the problem -- Pathophysiology -- Clinical manifestations and physical assessment -- Diagnostic evaluation -- Therapeutic approaches and nursing care -- Conclusion -- References -- 42: Superior vena cava syndrome / Heather L Brumbaugh -- Scope of the problem -- Physiological alterations -- Clinical manifestations -- Therapeutic approaches and nursing care -- Conclusion -- References -- 43: Syndrome of inappropriate antidiuretic hormone / AnnMarie K McDonnell Keenan -- Scope of the problem -- Etiology and risk factors -- Physiological alterations -- Clinical manifestations -- Assessment and grading -- Therapeutic approaches and nursing care -- Conclusion -- References -- 44: Tumor lysis syndrome / Jean Lydon -- Scope of the problem -- Classification and grading -- Physiological alterations -- Clinical manifestations -- Therapeutic approaches and nursing care -- Conclusion -- References -- Part 6: Care Of Individual With Specific Cancers -- 45: Aids-related malignancies / Sharon Steingass -- Introduction -- HIV disease and cancer -- Non-hodgkin's lymphoma -- Primary central nervous system lymphoma -- Kaposi sarcoma -- Cervical cancer -- Non-AIDS-defining malignancies -- Clinical trials and HIV -- Conclusion -- References -- 46: Bone and soft tissue sarcomas / Loleta C Samuel -- Introduction -- Epidemiology -- Etiology -- Screening and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Prognostic indicators -- Classification and staging -- Therapeutic approaches and nursing care -- Surgery -- Radiotherapy -- Chemotherapy -- Targeted therapy -- Description of selected sarcomas -- Symptom management and supportive care -- Future trends -- References -- 37: Bladder cancer / Gary Shelton -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 48: Breast cancer / Sara Bhagat Foxson; Jennie Greco Lattimer; Barbara Felder -- Introduction -- Epidemiology -- Etiology -- Prevention, screening and early detection -- Genetic counseling programs -- Pathophysiology -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Metastatic breast cancer -- Breast cancer in special populations -- Symptom management and supportive care -- Future trends -- Conclusion -- References -- 49: Central nervous system cancers / Terri Armstrong -- Introduction -- Brain tumors -- Epidemiology -- Etiology -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Spinal cord tumors -- Epidemiology -- Etiology -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 50: Cervical cancer / Virginia R Martin; Susan Vogt Temple -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Preinvasive disease -- Invasive disease -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 51: Colon, rectal, and anal cancers / Gail M Wilkes -- Colon cancer -- Introduction -- Epidemiology and etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Patient management and supportive care -- Conclusion -- Rectal cancer -- Introduction -- Epidemiology and etiology -- Prevention, screening, and early detection -- Pathophsiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- Anal cancer -- Introduction -- Epidemiology and etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 52: Endocrine malignancies / Colleen O'Leary -- Introduction -- Thyroid tumors -- Parathyroid tumors -- Pituitary tumors -- Adrenal tumors -- Multiple endocrine neoplasia -- Conclusion -- References -- 53: Endometrial cancer / Lois Almadrones Cassidy -- Introduction --Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 54: Esophageal cancer / Nancy D Tsottles -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References. 55: Gallbladder and bile duct cancer / Mary B Hodgin -- Gallbladder cancer -- Bile duct cancer -- Conclusion -- References -- 56: Head and neck malignancies / Ellen Carr -- Introduction -- Epidemiology -- Epidemiology -- Anatomy -- Etiology and risk factors -- Clinical manifestations -- Pathophysiology -- Assessment -- Imaging -- Classification and staging -- Therapeutic approaches -- Future treatment and management strategies -- Head and neck specialized programs of research excellence -- Treatment strategies for specific head and neck cancers -- Symptom management and supportive care -- Multidisciplinary care -- References -- 57: Leukemia and myelodysplastic syndromes / Sandra E Kurtin -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathobiology -- Classification and staging -- Clinical manifestations -- Assessment -- Therapeutic approaches and nursing management -- Symptom management and supportive care -- Conclusion -- References -- 58: Liver cancer / Nina N Grenon -- Introduction -- Epidemiology -- Etiology -- Prevention, screening and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 59: Lung cancer / Beth Eaby-Sandy -- Introduction -- Epidemiology -- Etiology -- Prevention -- Screening and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 60: Lymphomas / Sharon D Manson; Carlene Porter -- Introduction -- Lymphoid tissues and the immune system -- Diagnosis -- Hodgkin's disease -- Historical perspective -- Epidemiology -- Etiology -- Historical classification and patient presentation -- Treatment modalities -- Prognosis -- Non-hodgkin's lymphoma -- Historical perspective -- Epidemiology -- Etiology -- Histological classification systems -- Characteristics and management of B-cell NHL -- Posttransplant lymphoproliferative disorder -- Characteristics and management of T-cell NHL -- Treatment modalities -- Acute complications of therapy -- Chronic complication of therapy -- Nursing implications -- Conclusion -- References -- 61: Multiple myeloma / Joseph D Tariman; Beth Faiman -- Introduction -- Epidemiology -- Etiology -- Risk factors -- Prevention, screening, and early detection -- Pathophsiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and nursing care -- Conclusion -- References -- 62: Ovarian cancer / Virginia R Martin -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Continuity of care -- Future trends -- References -- 63: Pancreatic cancer / Mary B Hodgin -- Introduction -- Epidemiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and nursing care -- Future trends -- References -- 64: Prostate cancer / Meredith Wallace Kazer; Ashley Somerset Harmon -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 65: Renal cancer / Laura W Wood -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Conclusion -- References -- 66: Skin cancer / Suzanne M Mahon; Susan Germann Yackzan -- Introduction -- Epidemiology -- Etiology -- Calculating melanoma risk -- Prevention -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Conclusion -- References -- 67: Stomach cancer / Marcia Mickle -- Introduction -- Epidemiology -- Ethiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 68: Testicular germ cell cancer / Eric Zack -- Introduction -- Epidemiology -- Etiology -- Prevention, screening, and early detection -- Pathophysiology -- Clinical manifestations -- Assessment -- Classification and staging -- Therapeutic approaches and nursing care -- Symptom management and supportive care -- Conclusion -- References -- 69: Vulvar and vaginal cancer / Karen Olezewski -- Introduction -- Vulvar cancer -- Vaginal cancer -- Conclusion -- References -- Part 7: Dimensions Of Cancer Survivorship -- 70: Cancer survivorship: a critical aspect of care / Victoria Wochna Loerzel; Karen Meneses -- Introduction -- Overview of cancer survivorship -- Late effects in cancer survivors -- Psychosocial late effects in cancer survivors -- Special populations of cancer survivors -- Cancer survivorship care planning -- Health promotion among cancer survivors -- Social issues -- Advocacy -- Cancer survivorship research -- Conclusion -- References -- 71: Late effects of cancer treatment / Wendy Landier; Sonia Smith -- Introduction -- Overview of late effects following cancer treatment -- Late effects in specific populations of cancer survivors -- Providing clinical care for cancer survivors -- Survivorship care plan -- Resources -- Conclusion -- References -- 72: Family and caregiver issues / Laurel Northouse; Lixin Song -- Introduction -- Why help families of patients with cancer? -- Barriers to helping families of patients with cancer -- Theoretical perspective -- Effect of cancer on the quality of life of family members -- Practical strategies for helping patients and family members -- Conclusion -- References -- 73: Spiritual responses to cancer / Elizabeth Johnston Taylor -- Introduction -- Definitions -- Why address spirituality? -- Spirituality throughout the cancer experience -- Caregiver perspectives -- Providing spiritual care -- Conclusion -- References -- Part 8: Palliative Care And End Of Life -- 74: Principles and issues in palliative care / Peg Esper -- Introduction -- Historical perspectives -- Models of palliative care -- Barriers to providing quality palliative care -- Lack of evidenced-based interventions -- Ethical and legal issues in palliative care -- Challenges for the future of palliative care -- Conclusion -- References -- 75: Care during the final day of life / Judith A Paice -- Introduction -- Symptoms during the final days of life -- Difficult situations -- Patient and family education -- Conclusion -- References -- Part 9: Professional Issues For The Cancer Nurse -- 76: Advanced oncology practice nurse / Janet S Fulton -- Introduction -- Advanced practice nursing defined -- Advanced practice in oncology specialty -- Oncology advanced practice nursing education -- Regulation of advanced oncology nursing practice -- Economics and advanced oncology practice -- Implementing advanced oncology nursing practice: working collaboratively -- Challenges for the future -- Conclusion -- References -- Appendix A: Oncology clinical nurse specialist practice competencies -- Appendix B: Oncology nurse practitioner competencies -- 77: Legal issues / Lisa C Schulmeister -- Introduction -- Patient safety -- Chemotherapy medication errors -- Hypersensitivity and infusion-related reactions -- Vesicant extravasation -- Responding to errors and adverse events -- Risk management -- Complaints and litigation -- Privacy protection -- Telephone and electronic communication -- Pain management -- Conclusion -- References -- Index.