Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk - no matter how small - must be considered, assessed, and properly mitigated. If the science is not safe, it is not good science. Now in its fifth edition, Biological Safety: Principles and Practices remains the most comprehensive biosafety reference. This book presents the guiding principles of laboratory safety, including the identification, assessment, and control of the board variety of risks encountered in laboratories, production facilities, classrooms, and other unique environments. Specifically, Biological Safety covers: protection and control elements, ranging from biological safety cabinets and personal protection systems to workplace practices and decontamination methods; administrative controls in biorisk management, including regulations, guidelines, and compliance; various aspects of risk assessment, including bacterial, viral, mycotic, zoonotic, and molecular agents; protozoa and helminths; viral vectors, allergens, and toxins; and decontamination, aerobiology, occupational medicine, and training topics. A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological Safety is also a critical reference for laboratory managers and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses. -- from back cover.

Section I : Hazard identification. The microbiata of humans and microbial virulence factors / Paul A. Granato -- Indigenous zoonotic agents of research animals / Lon V. Kendall -- Biological safety considerations for plant pathogens and plant-associated microorganisms of significance to human health / Anne K. Vidaver, Sue A. Tolin, and Patricia Lambrecht -- Laboratory-associated infections / Karen Brandt Byers and A. Lynn Harding -- Section II : Hazard assessment. Risk assessment of biological hazards / Dawn P. Wooley and Diane O. Fleming -- Protozoa and helminths / Barbara L. Herwaldt -- Mycotic agents / Wiley A. Schell -- Bacterial pathogens / Travis R. McCarthy [and 3 others] -- Viral agents of human disease : biosafety concerns / Michelle Rozo, James Lawler, and Jason Paragas -- Emerging considerations in virus-based gene transfer systems / J. Patrick Condreay, Thomas A. Kost, and Claudia A. Mickelson -- Biological toxins : safety and science / Joseph P. Kozlovac and Robert J. Hawley -- Molecular agents / Daown P. Wooley -- Biosafety for microorganisms transmitted by the airborne routs / Michael A. Pentella -- Cell lines : applications and biosafety / Glyn N. Stacey and J. Ross Hawkins -- Allergens of animal and biological systems / Wanda Phipatanakul and Robert A. Wood -- Section III : Hazard control. Design of biomedical laboratory and specialized biocontainment facilities / Jonathan T. Crane and Jonathan Y. Richmond -- Primary barriers and equipment-associated hazards / Elizabeth Gilman Duane and Richard C. Fink -- Primary barriers : biological safety cabinets, fume hoods, and glove boxes / David C. Eagleson [and 4 others] -- Arthropod vector biocontainment / Dana L. Vanlandinghm, Stephen Higgs, and Yan-Jang S. Huang -- Aerosols in the microbiology laboratory / Clare Shieber, Simon Parks, and Allan Bennett -- Personal respiratory protection / Nicole Vars McCullough -- Standard precautions for handling human fluids, tissues, and cells / Debra L. Hunt -- Decontamination in the microbiology laboratory / Matthew J. Arduino -- Packing and shipping biological materials / Ryan F. Relich and James W. Snyder -- Section IV : Administrative control. Developing a biorisk management program to support biorisk management culture / LouAnn C. Burnett -- Occupational medicine in a biomedical research setting / James M. Schmitt -- Measuring biosafety program effectiveness / Janet S. Peterson and Melissa A. Morland -- A "one-safe" approach : continuous safety training initiatives / Sean G. Kaufman -- Biosafety and biosecurity : regulatory impact / Robert J. Hawley and Theresa D. Bell Toms -- Section V : Special environments. Boilogical safety and security in teaching laboratories / Christopher J. Woolverton and Abbey K. Woolverton -- Biosafety in the pharmaceutical industry / Brian R. Petuch -- Biosafety considerations for large-scale processes / Mary L. Cipriano, Marian Downing, and Brian R. Petuch -- Veterinary diagnostic laboratories and necropsy / Timothy Baszler and Tanya Graham -- Special considerations for animal agriculture pathogen biosafety / Robert A. Heckert, Joseph P. Kozlavac, and John T. Balog -- Biosafety of plant research in greenhouses and other specialized containment facilities / Dann Adair [and 3 others] -- Biosafety guidelines for working with small mammals in a field environment / Darin S. Carroll, Danielle Tack, and Charles H. Calisher -- Components of a biosafety program for a clinical laboratory / Michael A. Pentella -- Safety considerations in the biosafety level 4 maximum-containment laboratory / David S. Bressler and Robert J. Hawley.