The book can stand on its own as a learning resource for professionals, or it can be used to supplement a college-level textbook for an introductory statistics course. It includes varied examples and problems using real sets of data. Each chapter typically starts with an important or interesting research question that an investigator has pursued. Reflecting the broad applicability of statistical reasoning, the problems come from a wide variety of disciplines, including engineering, life sciences, business, and economics, as well as international and historical examples.