Principles of laboratory medicine. Clinical chemistry and molecular diagnostics ; Analytical and clinical evaluation of methods ; Preanalytical variation ; Establishment and use of reference values ; Specimen collection, processing, and other preanalytical variables ; Quality management ; Principles of basic techniques and laboratory safety -- Analytical techniques and instrumentation. Optical techniques ; Electrochemistry and chemical sensors ; Electrophoresis ; Chromatography ; Mass spectrometry ; Enzyme and rate analysis ; Immunochemical techniques ; Automation ; Point-of-care testing -- Analytes. Amino acids, peptides, and proteins ; Serum enzymes ; Tumor markers ; Kidney function tests ; Carbohydrates ; Lipids, lipoproteins, apolipoproteins, and other cardiac risk factors ; Electrolytes and blood gases ; Hormones ; Catecholamines and serotonin ; Vitamins and trace elements ; Hemoglobin, iron, and bilirubin ; Porphyrins and porphyrias ; Therapeutic drug monitoring ; Clinical toxicology ; Toxic elements -- Pathophysiology. Diabetes mellitus ; Cardiovascular disease ; Kidney disease ; Physiology and disorders of water, electrolyte, and acid-base metabolism ; Liver disease ; Gastric, pancreatic, and intestinal function ; Bone and mineral metabolism ; Disorders of the pituitary gland ; Adrenal cortex ; Thyroid disorders ; Reproduction-related disorders ; Pregnancy and prenatal testing ; Newborn screening and inborn errors of metabolism ; Pharmacogenetics -- Molecular diagnostics. Molecular principles ; Molecular techniques ; Molecular applications.