This text uses a case-based approach to help students master the fundamentals of drug therapeutics. Students will learn the basics of common diseases and disorders and develop practical problem-solving skills for devising and implementing successful drug treatment regimens. Case studies integrated into each chapter illustrate key concepts and principles of therapeutics and give students practice in developing their own evidence-based therapeutic plans.

Sect. 1 : General principles -- Medication therapy management and assessment of therapy -- Interpretation of clinical laboratory tests -- Drug interactions -- Pharmacogenomics and personalized medicine -- Managing drug overdoses and poisonings -- End-of-life care -- Interprofessional educations and practice -- Sect. 2 : Cardiac and vascular disorders -- Dyslipidemias, atherosclerosis, and coronary heart disease -- Essential hypertension -- Peripheral vascular disorders -- Thrombosis -- Chronic stable angina -- Acute coronary syndrome -- Heart failure -- Cardiac arrhythmias -- Hypertensive crises -- Shock -- Sect. 3 : Pulmonary disorders -- Asthma -- Chronic obstructive pulmonary disease -- Acute and chronic rhinitis -- Cystic fibrosis -- Sect. 4 : Gastrointestinal disorders -- Nausea and vomiting -- Upper gastrointestinal disorders -- Lower gastrointestinal disorders -- Complications of end-stage liver disease. Sect. 5 : Renal disorders -- Acid-base disorders -- Fluid and electrolyte disorders -- Chronic kidney injury -- Acute kidney disease -- Renal dialysis -- Dosing of drugs in renal failure -- Sect. 6 : Immunologic disorders -- Drug hypersensitivity reactions -- Systemic lupus erythematosus -- Kidney and liver transplantation -- Sect. 7 : Nutrition issues -- Basics of nutrition and patient assessment -- Obesity -- Adult enteral nutrition -- Adult parenteral nutrition -- Sect. 8 : Dermatologic disorders -- Dermatotherapy and drug induced skin disorders -- Acne -- Psoriasis -- Photosensitivity, photoaging, and burn injuries -- Sect. 9 : Rheumatic and musculoskeletal disorders -- Osteoarthritis -- Rheumatoid arthritis -- Gout and hyperuricemia -- Connective tissue disorders -- Sect. 10 : Women's health -- Contraception -- Infertility -- Obstetric drug therapy -- Disorders related to the menstrual cycle -- The transition through menopause -- Sect. 11 : Endocrine disorders -- Thyroid disorders -- Diabetes mellitus -- Sect. 12 : Eye disorders -- Eye disorders -- Sect. 13 : Neurologic disorders -- Pain and its management -- Care of the critically ill adult -- Multiple sclerosis -- Headache -- Parkinson disease and other movement disorders -- Seizure disorders -- Ischemic and hemorrhagic stroke. Sect. 14 : Infectious disorders -- Principles of infectious diseases -- Antimicrobial prophylaxis for surgical procedures -- Vaccinations -- Central nervous system infections -- Endocarditis -- Respiratory tract infections -- Tuberculosis -- Infectious diarrhea -- Intra-abdominal infections -- Urinary tract infections -- Sexually transmitted diseases -- Osteomyelitis and septic arthritis -- Skin and soft tissue infections -- Prevention and treatment of infections in neutropenic cancer patients -- Pharmacotherapy of human immunodeficiency virus infection -- Opportunistic infections in HIV-infected patients -- Fungal infections -- Viral infections -- Viral hepatitis -- Parasitic infections -- Tick-borne diseases -- Sect. 15 : Psychiatric disorders and substance abuse -- Anxiety disorders -- Sleep disorders -- Schizophrenia -- Depressive disorders -- Bipolar disorders -- Developmental disorders -- Attention deficit hyperactivity disorder in children, adolescents, and adults -- Substance use disorders -- Tobacco use and dependence -- Sect. 16 : Hematology and oncology -- Anemias -- Neoplastic disorders and their treatment : general principles -- Adverse effects of chemotherapy and targeted agents -- Pediatric malignancies -- Adult hematologic malignancies -- Breast cancer -- Lung cancer -- Colorectal cancer -- Prostate cancer -- Hematopoietic cell transplantation -- Sect. 17 : Pediatrics -- Pediatric pharmacotherapy -- Pediatric fluid, electrolytes, and nutrition -- Common pediatric illnesses -- Neonatal therapy -- Care of the critically ill child -- Sect. 18 : Geriatric therapy -- Geriatric drug use -- Geriatric neurocognitive disorders -- Geriatric urologic disorders -- Osteoporosis.