'Biochemistry' reflects the revolution that has taken place in biomedical science, culminating in the human genome project. A key focus of this edition is the features of protein structure and function that have been revealed by gene sequencing.

Biochemistry: an evolving science -- Protein composition and structure -- Exploring proteins and proteomes -- DNA, RNA, and the flow of genetic information -- Exploring genes and genomes -- Exploring evolution and bioinformatics -- Hemoglobin: portrait of a protein in action -- Enzymes: basic concepts and kinetics -- Catalytic strategies -- Regulatory strategies -- Carbohydrates -- Lipids and cell membranes -- Membrane channels and pumps -- Signal-transduction pathways -- Metabolism: basic concepts and design -- Glycolysis and gluconeogenesis -- The citric acid cycle -- Oxidative phosphorylation -- The light reactions of photosynthesis -- The calvin cycle and the pentose phosphate pathway -- Glycogen metabolism -- Fatty acid metabolism -- Protein turnover and amino acid catabolism -- The biosynthesis of amino acids -- Nucleotide biosynthesis -- The biosynthesis of membrane lipids and steroids -- The integration of metabolism -- DNA replication, repair, and recombination -- RNA synthesis and processing -- Protein synthesis -- The control of gene expression in prokaryotes -- The control of gene expression in eukaryotes -- Sensory systems -- The immune system -- Molecular motors -- Drug development.