Use your knowledge of pharmacology to enhance oral care. This 6th Edition describes how to evaluate a patient's health and optimize dental treatment by factoring in the drugs they take. It explores the basic fundamentals of pharmacology, special topics such as pain control, fear and anxiety, and oral complications of cancer therapy, and most importantly, the actions of specific drug groups on the human body. Whether you're concerned about the drugs a patient is already taking or the drugs you prescribe for treatment, this book helps you reduce risk and provide effective dental care. Dental aspects of many drug classes are expanded to include antibiotics, analgesics, and anesthetics. The Nonopioid Analgesics chapter groups together non-opioid analgesics, nonsterioidal anti-inflammatory drugs, and antirheumatic and antigout drugs, making these easier to locate and study. Glossary of Abbreviations appendix includes the most common abbreviations used for drugs or conditions. An updated discussion of drug-drug interactions covers the harmful effects of mixing medications. Coverage of adverse effects and mechanisms of COX-2 inhibitors, antibiotic prophylaxis, and antiplaque agents explains the dental risks relating to common drug treatments.

pt. I. Principles of pharmacology. Pharmacodynamics: mechanisms of drug action / John A. Yagiela -- Pharmacokinetics: the absorption, distribution, and fate of drugs / John A. Yagiela -- Pharmacotherapeutics: the clinical use of drugs / John A. Yagiela and Frank J. Dowd -- Pharmacogenetics and pharmacogenomics / David W. Hein and Denis M. Grant. pt. II. Pharmacology of specific drug groups. Introduction to autonomic nervous system drugs / Peter W. Abel and Michael T. Piascik -- Adrenergic agonists / Yaping Tu, Michael T. Piascik, and Peter W. Abel -- Adrenergic antagonists / Michael T. Piascik and Peter W. Abel -- Cholinergic drugs / Frank J. Dowd -- Antimuscarinic drugs / Frank J. Dowd -- Drugs affecting nicotinic receptors / Xi-Qin Ding -- Introduction to central nervous system drugs / Vahn A. Lewis -- Psychopharmacology: antipsychotic and antidepressant drugs / Vahn A. Lewis -- Sedative-hypontics, antianxiety drugs, and centrally acting muscle relaxants / Joseph A. Giovannitti, Jr., and Paul A. Moore -- Anticonvulsants / Vahn A. Lewis -- Anti-Parkinson drugs / Vahn A. Lewis -- Local anesthetics / John A. Yagiela -- Principles of general anesthesia / John A. Yagiela and Daniel A. Haas -- Agents used in general anesthesia and sedation / Daniel A. Haas and John A. Yagiela -- Introduction to antinociceptive drugs / Hyungsuk Kim and Raymond A. Dionne -- Opioid analgesics and antagonists / Michael H. Ossipov, Gerald F. Gebhart, and Frank Porreca -- Nonopioid analgesics, nonsteroidal anti-inflammatory drugs, and antirheumatic and antigout drugs / Elliot V. Hersh, Paul J. Desjardins, Clarence L. Trummel, and Stephen A. Cooper -- Histamine and histamine antagonists / Clarence L. Trummel -- Drugs for treating orofacial pain syndromes / Robert L. Merrill -- Antiarrhythmic drugs / Frank J. Dowd -- Drugs used in heart failure / Frank J. Dowd -- Antianginal drugs / Eileen L. Watson and Frank J. Dowd -- Diuretic drugs / William B. Jeffries and Dennis W. Wolff -- Antihypertensive drugs / Frank J. Dowd and William B. Jeffries -- Lipid-lowering drugs / George A. Cook -- Antianemic and hematopoietic stimulating drugs / Barton S. Johnson -- Procoagulant, anticoagulant, and thrombolytic drugs / Barton S. Johnson -- Drugs acting on the respiratory system / Karen S. Gregson, Bruno Kreiner, and Jeffrey D. Bennett -- Drugs acting on the gastrointestinal tract / David H. Shaw -- Pituitary, thyroid, and parathyroid pharmacology / Gail T. Galasko -- Adrenal corticosteroids / Clarence L. Trummel -- Insulin, oral hypoglycemics, and glucagon / Gail T. Galasko -- Steroid hormones of reproduction and sexual development / Angelo J. Mariotti -- Principles of antibiotic therapy / Thomas J. Pallasch -- Antibacterial and antibiotic drugs / Thomas J. Pallasch -- Antifungal and antiviral agents / No-Hee Park and Mo K. Kang -- Immunotherapy / John A. Yagiela and Anahid Jewett -- Antineoplastic drugs / Kark K. Kwak, Linsey R. Curtis, and Mark M. Schubert -- Aliphatic alcohols / Frank J. Dowd -- Anticaries agents / Sarat Thikkurissy -- Antiplaque and antigingivitis agents / Angelo J. Mariotti -- Antiseptics and disinfectants / John A. Molinari. pt. III. Special subjects in pharmacology and therapeutics. Analgesic use for effective pain control / Paul J. Desjardins and Elliot V. Hersh -- Management of fear and anxiety / Daniel A. Haas -- Antibiotic prophylaxis / Thomas J. Pallasch -- Oral complications of cancer therapy / Rajesh V. Lalla, Michael T. Brennan, and Mark M. Schubert -- Drugs of abuse / Charles S. Bockman and Peter W. Abel -- Toxicology / Harrell E. Hurst and Michael D. Martin -- Geriatric pharmacology / Marc W. Heft and Angelo J. Mariotti -- Drugs for medical emergencies / Morton B. Rosenberg -- Prescription writing and drug regulations / Vahn A. Lewis -- Use of herbs and herbal dietary supplements in dentistry / Richard P. Cohan and Mark Blumenthal -- Appendixes : 1. Drug interactions in clinical dentistry ; 2. Glossary of abbreviations. Introduction to autonomic nervous system drugs -- Adrenergic agonists -- Adrenergic antagonists -- Cholinergic drugs -- Antimuscarinic drugs -- Drugs affecting nicotinic receptors -- Introduction to central nervous system drugs -- Psychopharmacology : antipsychotic and antidepressant drugs -- Sedative-hypnotics, antianxiety drugs, and centrally acting muscle relaxants -- Anticonvulsants -- Anti-parkinson drugs -- Local anesthetics -- Principles of general anesthesia -- Agents used in general anesthesia and sedation -- Introduction to antinociceptive drugs -- Opioid analgesics and antagonists -- Nonopioid analgesics, nonsteroidal anti-inflammatory drugs, and antirheumatic and antigout drugs -- Histamine and histamine antagonists -- Drugs for treating orofacial pain syndromes -- Antiarrhythmic drugs -- Drugs used in heart failure -- Antianginal drugs -- Diuretic drugs -- Antihypertensive drugs -- Lipid-lowering drugs -- Antianemic and hematopoietic stimulating drugs -- Procoagulant, anticoagulant, and thrombolytic drugs -- Drugs acting on the respiratory system -- Drugs acting on the gastrointestinal tract -- Pituitary, thyroid and parathyroid pharmacology -- Adrenal corticosteroids -- Insulin, oral hypoglycemics and glucagon -- Steroid hormones of reproduction and sexual development -- Principles of antibiotic therapy -- Antibacterial and antibiotic drugs -- Antifungal and antiviral agents -- Immunotherapy -- Antineoplastic drugs -- Aliphatic alcohols -- Anticaries agents -- Antiplaque and antigingivitis agents -- Antiseptics and disinfectants. Analgesic use for effective pain control -- Management of fear and anxiety -- Antibiotic prophylaxis -- Oral complications of cancer therapy -- Drugs of abuse -- Toxicology -- Geriatric pharmacology -- Drugs for medical emergencies -- Prescription writing and drug regulations -- Use of herb and herbal dietary supplement in dentistry -- Drug interactions in clinical dentistry.