In this continuation of the Spy Kids saga, Juni Cortez has now retired from being a spy and is trying to live a normal life, while Carmen is still with OSS. When his sister Carmen is trapped inside a groundbreaking new video game, the only way to free her is to enter the game's virtual world and make it to the highest level. Juni goes in to rescue her, and together, the Spy Kids battle through tougher and tougher levels of the game, overcoming challenges with the help of other trapped players. They successfully shut down the game, but some of the games creatures escape into the real world. A power hungry villain called the Toymaker designed the game, and the whole family must unite to dispatch him.

Originally produced as a motion picture in 2003.