Pongo and Perdita have a litter of 15 Dalmatian puppies. Cruella De Vil takes a fancy to the puppies and tries to buy them from their human owners, Roger and Anita. Cruella wants to get a hold of those puppies, as well as more puppies, to make herself a lovely dalmatian skin coat. She hires some thugs to kidnap the puppies and hold them at an abandoned mansion. Now Pongo and Perdita must use an animal communication system to help find all the puppies.

Based on the book "The one hundred and one dalmatians" by Dodie Smith. Originally produced as a motion picture in 1961. Special features on disc one: All-new digital restoration with enhanced picture and sound; 101 pop-up trivia games for the family and for the fan; all-new "Cruella De Vil" music video (4 min.) -- On disc two: "Redefining the line: the making of One hundred and one Dalmatians" (34 min.); "Cruella De Vil: drawn to be bad" (7 min.); "Sincerely yours, Walt Disney" (13 min.); trailers, radio & TV spots; art galleries; music & more (deleted songs, alternate versions: 37 min.); games & activities.

Special features: Full-screen version -- "Cruella De Vil" music video -- Virtual Dalmatians game -- Pop-up trivia facts -- One hundred and one Dalmatians fun with language games -- Redefining the line: The making of One Hundred and One Dalmatians -- "Sincerely yours, Walt Disney" -- Cruella De Vil: Drawn to be bad -- Deleted songs -- Language: English 5.1 Disney enhanced home theater mix ; French ; Spanish -- Subtitles: English, French, Spanish.