With the 13th edition of Wintrobe's Clinical Hematology, this new edition once again bridges the gap between the clinical practice of hematology and the basic foundations of science. Broken down into eight parts, this book provides readers with a comprehensive overview of: Laboratory Hematology, The Normal Hematologic System, Transfusion Medicine, Disorders of Red Cells, Hemostasis and Coagulation; Benign Disorders of Leukocytes, The Spleen and/or Immunoglobulins; Hematologic Malignancies, and Transplantation. Within these sections, there is a heavy focus on the morphological exam of the perip.

Clinical Hematology; CONTRIBUTORS; PREFACE; ACKNOWLEDGMENTS; CONTENTS; PART I Laboratory Hematology; Examination of the Blood and Bone Marrow; Clinical Flow Cytometry; Cytogenetics; Molecular Diagnosis in Hematology; PART II The Normal Hematologic System; SECTION 1: Hematopoiesis; Origin and Development of Blood Cells; SECTION 2: The Erythrocyte; The Birth, Life, and Death of Red Blood Cells: Erythropoiesis, The Mature Red Blood Cell, and Cell Destruction; SECTION 3: Granulocytes and Monocytes; Neutrophilic Leukocytes; The Human Eosinophil. Mast Cells and Basophils: Ontogeny, Characteristics, and Functional DiversityMonocytes, Macrophages, and Dendritic Cells; SECTION 4:The Lymphocytes; Lymphocytes and Lymphatic Organs; B Lymphocytes; T Lymphocytes and Natural Killer Cells; Effector Mechanisms In Immunity; SECTION 5: HEMOSTASIS; Megakaryocytes; Platelet Structure and Function in Hemostasis and Thrombosis; Platelet Function in Hemostasis and Thrombosis; Blood Coagulation And Fibrinolysis; Endothelium: Angiogenesis and the Regulation of Hemostasis; PART III Transfusion Medicine; Red Cell, Platelet, and White Cell Antigens. Transfusion MedicinePART IV Disorders of Red Cells; SECTION 1: Introduction; Anemia:General Considerations; SECTION 2: Disorders of Iron Metabolismand Heme Synthesis; Iron Deficiency and Related Disorders; Sideroblastic Anemias; Hemochromatosis; Porphyrias; SECTION 3: Hemolytic Anemia; Hereditary Spherocytosis, Hereditary Elliptocytosis, And Other Disorders Associated With Abnormalities Of The Erythrocyte Membrane; Hereditary Hemolytic Anemias Due to Red Blood Cell Enzyme Disorders; Autoimmune Hemolytic Anemia; Hemolytic Disease of the Fetus and Newborn; Paroxysmal Nocturnal Hemoglobinuria. Acquired Nonimmune Hemolytic DisordersSECTION 4: Hereditary Disorders ofHemoglobin Structure and Synthesis; Sickle Cell Anemia and Other Sickling Syndromes; Thalassemias and Related Disorders: Quantitative Disorders of Hemoglobin Synthesis; Hemoglobins with Altered Oxygen Affinity, Unstable Hemoglobins, M-Hemoglobins, and Dyshemoglobinemias; SECTION 5: Other Red Cell Disorders; Megaloblastic Anemias:Disorders Of Impaired Dna Synthesis; Inherited Aplastic Anemia Syndromes; Acquired Aplastic Anemia; Red Cell Aplasia: Acquired And Congenital Disorders; Congenital Dyserythropoietic Anemias. Anemias Secondary to Chronic Disease and Systemic DisordersAnemias During Pregnancy and the Postpartum Period; Anemias Unique to the Fetus and Neonate; Erythrocytosis; PART V Disorders of Hemostasis and Coagulation; SECTION 1: Introduction; Diagnostic Approach to the Bleeding Disorders; SECTION 2: Thrombocytopenia; Thrombocytopenia: Pathophysiology and Classification; Thrombocytopenia Caused by Immunologic Platelet Destruction; Thrombotic Thrombocytopenic Purpura, Hemolytic-Uremic Syndrome, and Related Disorders; Miscellaneous Causes of Thrombocytopenia.