Featuring hundreds of full-color photomicrographs, this book prepares you for a job in the clinical lab by exploring the essential aspects of hematology. It shows how to accurately identify cells, simplifies hemostasis and thrombosis concepts, and covers normal hematopoiesis through diseases of erythroid, myeloid, lymphoid, and megakaryocytic origins. This book also makes it easy to understand complementary testing areas such as flow cytometry, cytogenetics, and molecular diagnostics. Well-known authors Bernadette Rodak, George Fritsma, and Elaine Keohane cover everything from working in a hematology lab to the parts and functions of the cell to laboratory testing of blood cells and body fluid cells. New content is added on basic cell biology and etiology of leukocyte neoplasias. Updated Molecular Diagnostics chapter keeps you current on techniques being used in the lab. Simplified hemostasis material ensures that you can understand this complex and important subject. Coverage of morphologic alteration of monocytes/macrophages is condensed into a table, as the disorders in this grouping are more of a biochemical nature with minimal hematologic evidence.

pt. 1: Introduction to hematology. An overview of clinical laboratory hematology ; Safety in the hematology laboratory ; Specimen collection ; Care and use of the microscope ; Quality assurance in hematology and hemostasis testing -- pt. 2: Hematopoiesis. Cellular structure and function ; Hematopoiesis ; Erythrocyte production and destruction ; Energy metabolism and membrane physiology of the Erythrocyte ; Hemoglobin metabolism ; Iron metabolism ; Leukocyte development, kinetics and functions ; Platelet production, structure, and function -- pt. 3: Routine laboratory evaluation of blood cells. Routine and point-of-care testing in hematology: manual and semiautomated methods ; Examination of the peripheral blood film and correlation with the complete blood count ; Bone marrow examination ; Body fluids in the hematology laboratory -- pt. 4: Hematopathology: erythrocyte disorders. Anemias: red blood cell morphology and approach to diagnosis ; Disorders of iron and heme metabolism ; Anemias caused by defects of DNA metabolism ; Bone marrow failure ; Introduction to increased destruction of erythrocytes ; Intrinsic defects leading to increased erythrocyte destruction ; Extrinsic defects leading to increased erythrocyte destruction- nonimmune causes ; Extrinsic defects leading to increased erythrocyte destruction- immune causes ; Hemoglobinopathies (structural defects in hemoglobin) ; Thalassemias -- pt. 5: Leukocyte disorders. Nonmalignant leukocyte disorders ; Introduction to leukocyte neoplasms ; Cytochemistry ; Cytogenetics ; Molecular diagnostics in the clinical laboratory ; Flow cytometric analysis in hematologic disorders ; Myeloproliferative neoplasms ; Myelodysplastic syndromes ; Acute leukemias ; Mature lymphoid neoplasms -- pt. 6: Hematology in selected populations. Pediatric and geriatric hematology -- pt. 7: Cell counting automation. Automated cell counting instrumentation -- pt. 8: Hemostasis and thrombosis. Normal hemostasis and coagulation ; Hemorrhagic coagulation disorders ; Thrombosis risk testing ; Thrombocytopenia and thrombocytosis ; Qualitative disorders of platelets and vasculature ; Laboratory evaluation of hemostasis ; Monitoring antithrombotic therapies ; Coagulation instrumentation.